Michael Andreeff, M.D., Ph.D.
Michael Andreeff is Professor of Medicine, Chief, Section of Molecular Hematology and Therapy, and holds the Paul and Mary Haas Chair in Genetics at MD Anderson Cancer Center. He is an international leader in the area of malignant hematology and experimental therapeutics. Dr. Andreeff received his medical degree and doctorate from the University of Heidelberg, Germany, and additional training and faculty appointments at the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York in the Departments of Pathology and Leukemia. Dr. Andreeff has been a pioneer in flow cytometry since 1971, when he established the first flow cytometry laboratory at the University of Heidelberg and organized the first European conference on flow cytometry. In 1977 he joined Memorial Sloan-Kettering Cancer Center, became head of the Leukemia Cell Biology and Hematopathology flow cytometry laboratory, organized the first Clinical Cytometry Conference in 1986 and the first Molecular Cytogenetics Conference in 1990. He has received uninterrupted NCI funding for over 30 years including as PI of SPORE, P01, R01 and R21 grants in the area of leukemia and lymphoma. He has published over 450 peer-reviewed papers, 5 books and 75 book chapters. Dr. Andreeff’s group has worked extensively on drug resistance in hematopoietic malignancies and breast cancer and developed or co-developed several new therapeutic agents including the novel triterpenoids CDDO and CDDO-Me and Bcl-2, XIAP, survivin, MEK and HDM2 inhibitors. Over the last decade, his group has made major contributions to the understanding of micro-environment-mediated drug resistance and developed strategies to exploit the underlying mechanisms for the treatment of hematopoietic and epithelial malignancies.